BLAST EXPOSURE DYSREGULATES NIGHTTIME MELATONIN SYNTHESIS AND SIGNALING IN THE PINEAL GLAND: A POTENTIAL MECHANISM OF BLAST-INDUCED SLEEP DISRUPTIONS

Blast-induced traumatic brain injury (bTBI) frequently results in sleep-wake disturbances.However, limited studies have investigated the molecular signaling mechanisms underlying these sleep disturbances, and potentially efficacious therapies are lacking.We investigated the levels of melatonin and genes involved in melatonin synthesis pathway in th

Abstract We Womens Shacket study aspects of entanglement and extremal surfaces in various families of spacetimes exhibiting cosmological, Big-Crunch, singularities, in particular isotropic AdS Kasner.The classical extremal surface dips into the bulk radial and time directions.Explicitly analysing the extremization equations in the semiclassical reg

Purpose.The need to replace the outdated element base of locomotive electrical apparatuses is urgent under conditions of locomotive overhaul to extend their service Wooden Bottle Opener Keychain life.The main aim of the work is to reduce costs for the operation and repair of rolling stock by increasing the reliability of electrical apparatuses, the